Bacteriophages isolated from dairy farm mitigated Klebsiella pneumoniae-induced inflammation in bovine mammary epithelial cells cultured in vitro.

Yuxiang ShiWenpeng ZhaoGang LiuTariq AliPeng ChenYongxia LiuJohn P KastelicBo HanJian Gao

Published in: BMC veterinary research (2021)

Bacteriophages CM8-1 and SJT-2 mitigated K. pneumoniae-induced inflammation in bMECs cultured in vitro. Therefore, the potential of these bacteriophages for treating mastitis in cows should be determined in clinical trials.

Keyphrases

klebsiella pneumoniae
high glucose
oxidative stress
clinical trial
diabetic rats
endothelial cells
escherichia coli
multidrug resistant
drug induced
risk assessment
climate change
human health
open label
stress induced