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Inflammatory profile in patients with rheumatoid arthritis and sarcopenia.

Mariel Lozada-MelladoLuis LlorenteAndrea Hinojosa-AzaolaMidori Ogata-MedelRaymundo David Valdez-EcheverríaAna Rosalía Lira-ReyesCastillo-Martínez Lilia
Published in: Clinical rheumatology (2024)
Patients with RA and sarcopenia were older and exhibited longer disease duration and higher levels of inflammatory cytokines compared to those without sarcopenia. These findings suggest potential implications for clinical outcomes. Key Points • The prevalence of sarcopenia in women with rheumatoid arthritis was 15.8% (95% CI, 8.9-18.2). • Levels of IL-1α, IL-6, and TNFβ cytokines were significantly higher in women with rheumatoid arthritis and sarcopenia compared with those without sarcopenia, adjusted for BMI, age, and disease duration.
Keyphrases
  • rheumatoid arthritis
  • community dwelling
  • skeletal muscle
  • disease activity
  • ankylosing spondylitis
  • oxidative stress
  • body mass index
  • risk factors
  • interstitial lung disease
  • physical activity
  • middle aged
  • human health