Prognostic and predictive value of angiogenesis-associated serum proteins for immunotherapy in esophageal cancer.

Mengting Gao Xueying WuXi JiaoYing HuYanni WangNa ZhuoFengxiao DongYujiao WangFengyuan WangYanshuo CaoChang LiuJian LiLin ShenHenghui ZhangZhihao Lu

Published in: Journal for immunotherapy of cancer (2024)

An angiogenesis-related risk score based on three proteins (IL-8, TIE2, and HGF) could predict ICI response and prognosis in patients with esophageal cancer, which warrants verification in the future. Our study highlights the potential application of combining ICIs and antiangiogenic therapy and supports Olink plasma protein sequencing as a liquid biopsy method for biomarker exploration.

Keyphrases

endothelial cells
vascular endothelial growth factor
wound healing
single cell
current status
ultrasound guided
ionic liquid
protein protein
binding protein
mesenchymal stem cells
fine needle aspiration