Application of a Volumetric Absorptive Microsampling (VAMS)-Based Method for the Determination of Paracetamol and Four of its Metabolites as a Tool for Pharmacokinetic Studies in Obese and Non-Obese Patients.

Laura Boffel Lisa Delahaye Luc De Baerdemaeker Christophe Pol Stove

Published in: Clinical pharmacokinetics (2022)

We demonstrated that finger-prick sampling is a viable alternative to conventional venous blood sampling to investigate the PK of APAP and its metabolites in obese and non-obese patients.

Keyphrases

obese patients
bariatric surgery
ms ms
gastric bypass
roux en y gastric bypass
weight loss
solid phase extraction
metabolic syndrome
case control
mass spectrometry