Clinical and molecular characterization of a multi-institutional cohort of pediatric spinal cord low-grade gliomas.

Sydney T GrobLiana NobreKristen R CampbellKurtis D DaviesScott RyallDara L AisnerLindsey HoffmanShadi ZahediAndrew MorinMichele CrespoAnandani NellanAdam L GreenNicholas ForemanRajeev VibhakarTodd C HankinsonMichael H HandlerCynthia HawkinsUri TaboriB K Kleinschmidt-DeMastersJean M Mulcahy Levy

Published in: Neuro-oncology advances (2020)

KIAA1549-BRAF was seen in higher frequency than BRAF V600E or other genetic aberrations in pediatric spinal LGGs and experienced lower death rates compared to KIAA1549-BRAF negative patients, although this was not statistically significant.

Keyphrases

low grade
spinal cord
high grade
end stage renal disease
metastatic colorectal cancer
ejection fraction
chronic kidney disease
wild type
spinal cord injury
prognostic factors
peritoneal dialysis
copy number
neuropathic pain
gene expression
patient reported outcomes