Classical celiac disease is more frequent with a double dose of HLA-DQB1*02: A systematic review with meta-analysis.

Judit BajorPéter HegyiNelli FarkasPéter HegyiAnita IllésMargit SolymárErika PéterváriMárta BalaskóGabriella PárPatrícia SarlósÁkos SzűcsJózsef CzimmerKata SzemesOrsolya HuszárPéter VarjúÁron Vincze

Published in: PloS one (2019)

A double dose of HLA-DQB1*02 gene seems to predispose patients to developing classical CD and villous atrophy. Risk stratification by HLA-DQB1*02 gene dose requires further clarification due to the limited available evidence.

Keyphrases

celiac disease
end stage renal disease
ejection fraction
genome wide
copy number
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
genome wide identification
patient reported outcomes
dna methylation
transcription factor