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Can Metabolite and Hormone Profiles Provide a Rationale for Choosing Between Bariatric Procedures?

Marta GuimarãesSofia S PereiraJens J HolstMário NoraMariana P Monteiro
Published in: Obesity surgery (2021)
Post-prandial metabolite excursions diverge across bariatric procedures being lowest after BPD-DS, intermediate after SADI-S, and highest after RYGB, in parallel with the anti-diabetic efficacy and malabsorption risk reported for each type of intervention. SADI-S and RYGB-M seem to elicit similar post-prandial hormonal profiles, with potentially lower risk of protein malnutrition when compared to BPD-DS. Post-absorptive metabolite and hormone profiles could provide a rationale as decision-aid when choosing among bariatric surgery interventions, as long as these findings are validated in future trials.
Keyphrases
  • roux en y gastric bypass
  • weight loss
  • bariatric surgery
  • obese patients
  • gastric bypass
  • clinical trial
  • type diabetes
  • physical activity
  • metabolic syndrome
  • adipose tissue
  • current status
  • small molecule
  • skeletal muscle