Concentration and Glycoform of Rituximab in Plasma of Patients with B Cell Non-Hodgkin's Lymphoma.

Atsushi YonezawaYuki OtaniToshiyuki KitanoMayuko MoriSho MasuiYui IsomotoMasahiro TsudaSatoshi ImaiYasuaki IkemiMasaya DendaYuki SatoShunsaku NakagawaTomohiro OmuraTakayuki NakagawaIkuko YanoMakoto HayakariAkifumi Takaori-KondoKazuo Matsubara

Published in: Pharmaceutical research (2019)

Inter-individual variations in plasma concentrations of rituximab were found in some B-NHL patients. We could analyze a change in glycoforms of rituximab in the patients, and this finding may affect the pharmacokinetics of rituximab.

Keyphrases

diffuse large b cell lymphoma
end stage renal disease
ejection fraction
newly diagnosed
hodgkin lymphoma
prognostic factors
chronic lymphocytic leukemia