The Critical Role of Spreading Depolarizations in Early Brain Injury: Consensus and Contention.
R David AndrewJed A HartingsCenk AyataK C BrennanKen D Dawson-ScullyEszter FarkasOscar HerrerasSergei A KirovMichael MüllerNikita Ollen-BittleClemens ReiffurthOmer RevahR Meldrum RobertsonC William ShuttleworthGhanim UllahJens P DreierPublished in: Neurocritical care (2022)
Finally, we summarize points of consensus and contention among the authors as well as where SD research may be heading. In an accompanying review, we critique the role of the glutamate excitotoxicity theory, how it has shaped SD research, and its questionable importance to the study of early brain injury as compared with SD theory.