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'Hybrid' oncocytoma: collecting duct (Bellini) carcinoma-the peril from this extremely rare intratumoural coexistence.

Ioannis TsikopoulosDimitrios Ioannis PapadopoulosKonstantinos CharitopoulosChrysovalantis Gkekas
Published in: BMJ case reports (2021)
We presented an extremely rare entity of 'hybrid' oncocytoma and collecting duct (Bellini) carcinoma. The intratumoural coexistence of benign and malignant cells may lead to false diagnosis and suboptimal treatment of an aggressive tumour. Diagnosis may be challenging if only based on imaging modalities. Even the established value of targeted renal biopsy may be questioned in such scarce cases. Consequently, active surveillance for small renal tumours shall not considered a widely safe management.
Keyphrases
  • induced apoptosis
  • high resolution
  • cell cycle arrest
  • cancer therapy
  • cell death
  • endoplasmic reticulum stress
  • signaling pathway
  • cell proliferation
  • drug delivery