Novel conjugated small molecule-based nanoparticles for NIR-II photothermal antibacterial therapy.
Wenying JiaFangfang HuangQiang ZhangLinlin ZhaoChenxi LiYan LuPublished in: Chemical communications (Cambridge, England) (2022)
Single organic small molecule-based nanoparticles (CNPs) with strong responses within the NIR-II (1000-1350 nm) bio-window were prepared, and successfully applied as a highly efficient photothermal antibacterial agent for the first time. CNPs exhibit an outstanding bacteria inhibition efficiency of almost 100% against Staphylococcus aureus ( S. aureus) with a high photothermal conversion efficiency (PTCE) of circa 49% under NIR-II laser irradiation (1064 nm) for 8 min.
Keyphrases
- photodynamic therapy
- small molecule
- highly efficient
- fluorescence imaging
- drug release
- staphylococcus aureus
- protein protein
- drug delivery
- silver nanoparticles
- cancer therapy
- anti inflammatory
- pseudomonas aeruginosa
- mass spectrometry
- radiation therapy
- biofilm formation
- wound healing
- bone marrow
- high speed
- radiation induced
- smoking cessation
- essential oil