PET imaging of [11C]PBR28 in Parkinson's disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding.
Katarina VarnäsZsolt CselényiAurelija JucaiteChrister HalldinPer SvenningssonLars FardeAndrea VarronePublished in: European journal of nuclear medicine and molecular imaging (2018)
The findings do not support the hypothesis of elevated cerebral TSPO binding or a relationship between TSPO binding and dopaminergic pathology in PD.