Circular RNA KIF4A Promotes Liver Metastasis of Breast Cancer by Reprogramming Glucose Metabolism.
Jun HuangXinpei DengXuedong ChenZaoshang ChangQuzhe LuAnliu TangPeng LiuPublished in: Journal of oncology (2022)
This study demonstrated that the circKIF4A-miR-335-OCT4/ALDOA-HK2/PKM2 axis is critical to breast cancer metabolic reprogramming, indicating that this axis could be a novel therapeutic target for the treatment of liver metastasis of breast cancer.