Suppressive role of vascular endothelial growth factor on intestinal apoptosis in induced necrotizing enterocolitis in rats.

Hee-Beom Yang Hyun-Young Kim Soo-Hong Kim So-Young Kim

Published in: Annals of surgical treatment and research (2023)

We identified apoptotic and inflammatory genes to confirm the preventive effect of VEGF pretreatment on NEC in rats. This study presents a novel approach to prevent apoptosis via VEGF pretreatment in rats with lipopolysaccharide/hypoxia-induced NEC.

Keyphrases

vascular endothelial growth factor
oxidative stress
cell death
endothelial cells
endoplasmic reticulum stress
cell cycle arrest
diabetic rats
toll like receptor
genome wide
gene expression
transcription factor
drug induced
stress induced