Impact of preoperative chemoradiation with higher dose intensity modulated radiotherapy on pathological complete response for locally advanced rectal cancer: a systematic review.

Roberta CarbonaraAlessia SurgoMaria Paola CilibertiFabiana GregucciIlaria BonaparteLuca NicosiaElisa MeldolesiMorena CaliandroValentina FerraroRiccardo InchingoloRiccardo MemeoElena LudovicoRoberto CalbiMariadea LavalleMaria Antonietta GambacortaFilippo AlongiAlba Fiorentino

Published in: Expert review of anticancer therapy (2022)

Radiotherapy dose intensification in LARC showed a slight increase of pCR compared to historical studies. Prospective evaluations are necessary to define which patients would benefit most.

Keyphrases

locally advanced
rectal cancer
early stage
end stage renal disease
radiation therapy
ejection fraction
chronic kidney disease
squamous cell carcinoma
radiation induced
prognostic factors
patients undergoing
peritoneal dialysis
real time pcr