Increased macrophage M2/M1 ratio is associated with intracranial aneurysm rupture.

Mária Hundža StratilováMiroslav KoblížekAnna ŠtekláčováVladimír BenešMartin SamešAleš HejčlJosef Zámečník

Published in: Acta neurochirurgica (2022)

The degree of inflammatory cell infiltration associated with a shift in macrophage phenotype towards M2 macrophages could play an important role in structural changes of the aneurysm wall leading to its rupture.

Keyphrases

coronary artery
adipose tissue
single cell
abdominal aortic aneurysm
cell therapy
oxidative stress
stem cells