T-SPOT.TB reactivity in Southern African children with and without in utero HIV exposure.

Saori C IwasePaul T EdlefsenLynnette BhebheKessy MotsumiSikhulile MoyoAnna-Ursula HappelDanica ShaoNicholas MmasaSara SchenkelMelanie A GasperMelanie DuboisMegan A FilesChetan SeshadriFergal DuffyJohn D AitchisonMihai G NeteaJennifer JaoDonald W CameronClive M GrayHeather B JaspanKathleen M Powis

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)

Infants HIV-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared TB infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU aged 9-18 months using T-SPOT.TB. Prevalence of TB infection was low and did not differ by HIV exposure status.

Keyphrases

hiv infected
antiretroviral therapy
hiv positive
human immunodeficiency virus
hiv testing
hepatitis c virus
hiv aids
mycobacterium tuberculosis
risk factors
young adults