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Lower retention after retrograde coronary venous infusion compared with intracoronary infusion of mesenchymal stromal cells in the infarcted porcine myocardium.

Wouter A GathierMira van der NaaldBas R van KlarenboschAnton E TuinenburgJohn Lm BemelmansKlaus NeefJoost Pg SluijterFrebus J van SlochterenPieter A DoevendansSteven A J Chamuleau
Published in: BMJ open science (2019)
RCVI is significantly less efficient in delivering cells to the heart compared with IC infusion. RCVI led to more procedure-related safety issues than IC infusion, with multiple cases of venous dissection and development of haematomas and pericardial fluid collections.
Keyphrases
  • low dose
  • heart failure
  • coronary artery
  • bone marrow
  • minimally invasive
  • signaling pathway
  • st elevation myocardial infarction
  • acute coronary syndrome
  • drug induced
  • endoplasmic reticulum stress
  • ejection fraction