Initial validation of the diagnostic performance of Thymic-Thoracic Ratio as a marker of conotruncal abnormalities and for prediction of surgical prognosis in fetuses without 22q11.2 deletion.
Giovanna Irene BattistoniGiovanni Delli CarpiniMassimo ColaneriRamona MontironiGiulia GelzoniLuca GiannellaStefano Raffaele GiannubiloMarco PozziAndrea CiavattiniPublished in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2020)
T-T ratio measurement could be useful to identify fetuses at higher risk of conotruncal heart diseases, even without chromosomic deletion, with a cutoff of 0.35. Since a lower T-T ratio seems to be related to a worse surgical neonatal prognosis, it could be possible to provide effective counseling and refer patients to high-specialized centers for fetal echocardiography and cardiac surgery.
Keyphrases
- cardiac surgery
- end stage renal disease
- chronic kidney disease
- ejection fraction
- newly diagnosed
- computed tomography
- heart failure
- spinal cord
- palliative care
- acute kidney injury
- prognostic factors
- left ventricular
- pulmonary hypertension
- spinal cord injury
- men who have sex with men
- human immunodeficiency virus
- hepatitis c virus