Interleukin-18 as a severity marker and novel potential therapeutic target for epidermolytic ichthyosis.
Osamu AnsaiToshinari MiyauchiRyota HayashiTatsuya KatsumiTomoki NishiguchiAkito HasegawaSatoru ShinkumaKen NatsugaToshifumi NomuraYutaka ShimomuraRiichiro AbePublished in: Clinical and experimental dermatology (2022)
Our results suggest that serum IL-18 is a severity marker released from the skin of patients with EI. Blockade of IL-18 may be a useful novel therapeutic option for patients with EI.
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