Gamma distribution model of diffusion MRI for evaluating the isocitrate dehydrogenase mutation status of glioblastomas.
Hanae TakaseOsamu TogaoKazufumi KikuchiNobuhiro HataRyusuke HataeToru ChikuiKenji TokumoriYukiko KamiDaisuke KugaYuhei SangatsudaMasahiro MizoguchiAkio HiwatashiKousei IshigamiPublished in: The British journal of radiology (2022)
Diffusion MRI based on the γ distribution model could well describe the pathological features of IDH-mutant and IDH-wildtype glioblastomas, and its use enabled the significant differentiation of these tumors. The γ distribution model may contribute to the non-invasive identification of the IDH mutation status based on histological viewpoint.