High incidence of glucocorticoid-induced hyperglycaemia in inflammatory bowel disease: metabolic and clinical predictors identified by machine learning.
Martin McDonnellRichard J HarrisFlorina BorcaTilly MillsLouise DowneySuranga DharmasiriMayank PatelBenjamin ZareMatt StammersTrevor R SmithRichard FelwickJ R Fraser CummingsHang T T PhanMarkus GwiggnerPublished in: BMJ open gastroenterology (2021)
Hyperglycaemia is common in IBD patients treated with intravenous GC. Therefore, CBG monitoring should be included in routine clinical practice. Machine learning methods can identify key risk factors for clinical complications. Steroid-sparing treatment strategies may be considered for those IBD patients with higher admission CRP and greater disease duration, who appear to be at the greatest risk of hyperglycaemia.