Factors Associated with Delirium in COVID-19 Patients and Their Outcome: A Single-Center Cohort Study.
Annabella Di GiorgioAntonio MirijelloClara De GennaroAndrea FontanaPaolo Emilio AlboiniLucia FlorioVincenzo InchingoloMichele ZarrelliGiuseppe MiscioPamela RaggiCarmen MarcianoAnnibale AntonioniSalvatore De CosmoFilippo AucellaAntonio GrecoMassimo CarellaMassimiliano CopettiMaurizio Angelo LeonePublished in: Diagnostics (Basel, Switzerland) (2022)
Delirium was the strongest predictor of poor outcome in COVID-19 patients, especially in the hypoactive subtype. Several clinical features and inflammatory markers were associated with the increased risk of its occurrence. The early recognition of these factors may help clinicians to select patients who would benefit from both non-pharmacological and pharmacological interventions in order to prevent delirium, and in turn, reduce the risk of admission to ICU or death.