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Biodistribution and dosimetry of 177 Lu-DOTA-IBA for therapy of bone metastases.

Hongmei LiWenjie PeiXiqun YangGengcuo QuQingchu HuaLin LiuYudi WangTingting XuYue Chen
Published in: EJNMMI research (2024)
Dosimetric results show that the ADs for critical organs and total body are within the safety limit and with high bone retention. It is a promising radiopharmaceutical alternative for the targeted treatment of bone metastases, controlling its progression, and improving the survival and quality of life of patients with advanced bone metastasis.
Keyphrases
  • bone mineral density
  • pet imaging
  • radiation therapy
  • soft tissue
  • bone loss
  • pet ct
  • cancer therapy
  • postmenopausal women
  • body composition
  • combination therapy
  • free survival