Application of Blood-Brain Barrier Permeability Imaging in Global Cerebral Edema.
Jana IvanidzeOmar N KallasAjay GuptaElizabeth K WeidmanHediyeh BaradaranD MirA E GiambroneAlan Z SegalJan ClaassenPina C SanelliPublished in: AJNR. American journal of neuroradiology (2016)
Extended CTP was used to evaluate blood-brain barrier permeability in patients with SAH with and without global cerebral edema. Kep is an important indicator of altered blood-brain barrier permeability in patients with decreased blood flow, as Kep is flow-independent. Further study of blood-brain barrier permeability is needed to improve diagnosis and monitoring of global cerebral edema.