Intestinal Flora is a Key Factor in Insulin Resistance and Contributes to the Development of Polycystic Ovary Syndrome.

Yue-Lian YangWei-Wei ZhouShan WuWen-Li TangZong-Wei WangZu-Yi ZhouZe-Wen LiQing-Fa HuangYan He Hong-Wei Zhou

Published in: Endocrinology (2021)

Bacteroides is a key microbial biomarker in PCOS and shows diagnostic value. Gut dysbiosis can cause insulin resistance. FXR activation might play a beneficial rather than detrimental role in glucose metabolism in PCOS.

Keyphrases

polycystic ovary syndrome
insulin resistance
adipose tissue
high fat diet
skeletal muscle
metabolic syndrome
type diabetes
high fat diet induced
weight loss