Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial.
Antony J CutlerJoao OliveiraRicardo C FerreiraBen ChallisNeil M WalkerSarah CaddyJia LuHelen E StevensDeborah J SmythMarcin L PekalskiJane KennetKara M D HunterIan GoodfellowLinda S WickerJohn A ToddFrank Waldron-LynchPublished in: Wellcome open research (2017)
The results illustrate the innate, adaptive and counter-regulatory immune responses to norovirus infection. Low-dose IL-2 administration induces many of the Treg responses observed during infection.