Metabolomic profiling of cardiac allografts after controlled circulatory death.
Thaïs HautbergueFlorent LaverdureSimon Dang VanAurelien ValleeMateo Sanchis-BorjaBenoît DecanteMaïra GaillardChristophe JunotFrançois FenailleOlaf MercierBenoit ColschJulien GuihairePublished in: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation (2023)
A specific metabolic profile was observed in DCD hearts, mainly characterized by an increased nucleotide catabolism. DCD and BSD metabolomes proved normalized during ESHP. Complementary investigations are needed to correlate these findings to cardiac performances.