Retrospective characterization of canine coagulopathies using the turbidimetric ACL-TOP 300 analyzer (2014-2015): Forty-seven dogs.
Rae RichardsonJeffrey M ToddLeslie C SharkeyRobert J WashabauKevin D WilliamsKim J LittleAaron RendahlPublished in: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) (2018)
The classically utilized indicators of secondary hemostasis, PT and aPTT, were prolonged within all 4 groups; DIC, LF, PHC and ROD as expected. Fibrinogen concentration was increased in both PHC and ROD, decreased in LF and increased but with a bimodal distribution in DIC that correlated with clinical bleeding. The degree of PT and aPTT prolongation did not correlate with clinical bleeding in the DIC group, however clot curve analysis, did reveal an association.