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Normalized grip strength is a sensitive outcome measure through all stages of Duchenne muscular dystrophy.

Jean-Yves HogrelValérie DecostreIsabelle LedouxMarie de AntonioErik H NiksImelda J M de GrootVolker StraubFrancesco MuntoniValeria RicottiThomas VoitAndreea SeferianLaurent ServaisLaurent Servais
Published in: Journal of neurology (2020)
Grip strength constitutes a sensitive and continuous outcome measure that can be used across all stages of DMD. Its measurement is easy to standardized, can be used in ambulatory and non-ambulatory patients and does not present any floor or ceiling effect. It is thus attractive as an outcome measure in therapeutic trials.
Keyphrases
  • duchenne muscular dystrophy
  • end stage renal disease
  • blood pressure
  • ejection fraction
  • chronic kidney disease
  • newly diagnosed
  • peritoneal dialysis
  • prognostic factors
  • muscular dystrophy
  • patient reported outcomes