Real-life implementation of a G6PD deficiency screening qualitative test into routine vivax malaria diagnostic units in the Brazilian Amazon (SAFEPRIM study).
José Diego de-Brito-SousaFelipe Leão Gomes MurtaSheila Vitor-SilvaVanderson de Souza SampaioMaxwell O MendesMarcelo A M BritoTalita S B BatistaAlicia Cacau Patrine Dos SantosLeonardo Lincoln Gomes MarquesLaila R A BarbosaMarly M MeloDjane C Baia-da-SilvaAlexandre V Silva-NetoThalie C SantosBrenda K A SouzaErick F G FigueiredoEmanuelle L SilvaSheila RodovalhoTheresa H NakagawaAna Ruth ArcanjoAndré Machado de SiqueiraGisely C MeloJudith RechtGonzalo J DomingoSozinho AcácioGermana BanconeWuelton M MonteiroMarcus Vinícius Guimarães de LacerdaPublished in: PLoS neglected tropical diseases (2021)
G6PD screening using the qualitative CareStart G6PD test performed by HCPs in MTUs of an endemic area showed high sensitivity and concerning low specificity. The amount of false G6PD deficiency detected led to substantial loss of opportunities for radical cure.