Incidence, clinicopathological characteristics, and therapeutic strategy for gastric cancer patients with metastasis to the central nervous system.

Tsutomu NamikawaAkira MaruiKeiichiro YokotaYasuhiro KawanishiMasaya MunekageSunao UemuraHiromichi MaedaHiroyuki KitagawaMichiya KobayashiKazuhiro Hanazaki

Published in: Asia-Pacific journal of clinical oncology (2022)

CNS metastasis was found in 2.9% (12/419) of patients with unresectable advanced or recurrent gastric cancer. Diffuse-type histology was a risk factor for CNS metastasis. Multidisciplinary treatment, including surgical resection, radiation treatment, or chemotherapy, for CNS metastasis from gastric cancer may benefit selected patients.

Keyphrases

blood brain barrier
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
combination therapy
quality improvement