Prostaglandin E2/EP2 receptor signalling pathway promotes diabetic retinopathy in a rat model of diabetes.

Man WangYangningzhi WangTianhua XiePengfei ZhanJian ZouXiaowei NieJun ShaoMiao ZhuangChengye TanJianxin TanYouai DaiJie SunJiantao LiYuehua LiQian ShiJing LengXiaolu WangYong Yao

Published in: Diabetologia (2018)

The PGE2/EP2R signalling pathway is involved in STZ-induced diabetic retinopathy and could be considered as a potential target for diabetic retinopathy prevention and treatment.

Keyphrases

diabetic retinopathy
optical coherence tomography
diabetic rats
type diabetes
cardiovascular disease
high glucose
oxidative stress
glycemic control
drug induced
metabolic syndrome
risk assessment
human health
climate change
binding protein
stress induced