Stem Cell-Based Tissue Engineering for Cleft Defects: Systematic Review and Meta-Analysis.
Diandra Sabrina Natsir KallaSalem A AlkaabiFaqi Nurdiansyah HendraNisrina Ekayani NasrunMuhammad RuslinTymour ForouzanfarMarco N HelderPublished in: The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association (2023)
AC and CP reconstructions are enhanced by addition of osteogenic cells to biomaterials. Directions and estimates of treatment effect are useful to predict therapeutic efficacy and guide future clinical trials of bone tissue engineering.
Keyphrases
- pi k akt
- tissue engineering
- cell cycle arrest
- signaling pathway
- stem cells
- induced apoptosis
- clinical trial
- cell proliferation
- mesenchymal stem cells
- bone marrow
- bone mineral density
- combination therapy
- magnetic resonance
- soft tissue
- endoplasmic reticulum stress
- oxidative stress
- open label
- postmenopausal women
- study protocol
- bone loss
- image quality
- phase iii