Identification of Novel Causal Blood Biomarkers Linking Metabolically Favorable Adiposity With Type 2 Diabetes Risk.

Marie PigeyreJennifer SjaardaShihong MaoMichael ChongSibylle HessSalim YusufUlagamadesan Venkatesan Guillaume Paré

Published in: Diabetes care (2019)

We identified IGFBP-3 as a novel biomarker linking a lack of favorable adiposity with type 2 diabetes risk and a predictive marker for incident cardiovascular events. Using IGFBP-3 blood concentrations may improve the risk assessment of cardiometabolic diseases.

Keyphrases

cardiovascular events
risk assessment
cardiovascular disease
coronary artery disease
insulin resistance
type diabetes
weight gain
adipose tissue
metabolic syndrome
body mass index
climate change
weight loss