Anticoagulation use and the risk of stroke and major bleeding in patients on hemodialysis: From the VIVALDI, a population-based prospective cohort study.

Oliver KönigsbrüggeHannah MeiselAljoscha BeyerSabine SchmaldienstRenate Klauser-BraunMatthias LorenzMartin AuingerJosef KletzmayrManfred HeckingWolfgang C WinkelmayerIrene LangIngrid PabingerMarcus SäemannCihan Ay

Published in: Journal of thrombosis and haemostasis : JTH (2021)

Although the nonrandomized nature of the study is prone to bias, anticoagulation with VKAs was not associated with decreased thromboembolic risk, but rather with increased risk of major bleeding and may be net harmful to patients with AF on HD.

Keyphrases

atrial fibrillation
end stage renal disease
chronic kidney disease
peritoneal dialysis
ejection fraction
newly diagnosed
venous thromboembolism
patient reported outcomes
blood brain barrier
brain injury