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Leveraging physiologically based pharmacokinetic modeling to optimize dosing for lopinavir/ritonavir with rifampin in pediatric patients.

Sara N SalernoEdmund V CapparelliHelen M McIlleronJacqueline G GerhartJulie B DumondAngela D M KashubaPaolo DentiDaniel Gonzalez
Published in: Pharmacotherapy (2022)
Super-boosted LPV/RTV with 15 mg/kg rifampin achieves therapeutic LPV troughs in HIV/TB-infected simulated children.
Keyphrases
  • antiretroviral therapy
  • hiv infected
  • hiv positive
  • human immunodeficiency virus
  • hiv testing
  • hiv aids
  • young adults
  • mycobacterium tuberculosis
  • hepatitis c virus
  • men who have sex with men
  • south africa