Human herpesvirus 8 infection is associated with prostate cancer among IFNL4-ΔG carriers.
Frank J JenkinsTsion Z MinasWei TangTiffany H DorseyStefan AmbsPublished in: Prostate cancer and prostatic diseases (2022)
HHV-8 seropositivity is associated with increased odds of prostate cancer in men harboring the IFNL4 rs368234815-ΔG variant. This study describes HHV-8 infection as a candidate prostate cancer risk factor in men with the IFNL4-ΔG genotype and supports the hypothesis that IFNL4-ΔG is a susceptibility factor that contributes to prostate cancer.