Integration of transcriptome and proteome profiles in glioblastoma: looking for the missing link.
Jean-Michel LeméeAnne ClavreulMarc AubryEmmanuelle ComMarie de TayracJean MosserPhilippe MeneiPublished in: BMC molecular biology (2018)
In this study, we showed a low correlation between transcriptome and proteome data for GB samples as described in other cancer tissues. We observed that NEFL, SYN1 and 12 biological processes were deregulated in both the transcriptome and proteome data. It will be important to analyze more specifically these processes and these two proteins to allow the identification of new theranostic markers or potential therapeutic targets for GB.