Diagnosis of Coxiella burnetii Prosthetic Joint Infection Using mNGS and ptNGS: A Case Report and Literature Review.
Chang-Yu HuangHaiqi DingYiming LinZeyu ZhangXinyu FangYanshu ChenYang ChenYuan-Qing CaiWen-Bo LiWen-Ming ZhangZi-da HuangPublished in: Orthopaedic surgery (2022)
The symptoms of C. burnetii PJI may be different from those of Q fever, which may lead to misdiagnosis. mNGS and ptNGS may be helpful for the identification of C. burnetii. Once the diagnosis of C. burnetii PJI is confirmed, doxycycline in combination with a fluoroquinolone can be effectively administered after revision surgery.