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Hospitalizations for infections in primary Sjögren's syndrome patients: a nationwide incidence study.

Radjiv GoulabchandAlain MakinsonJacques MorelPhiline Witkowski-Durand-VielNicolas NagotPaul LoubetCamille RoubilleDanièle NoelDavid MorquinKim HenryThibault MuraPhilippe Guilpain
Published in: Annals of medicine (2022)
pSS patients are at higher risk of hospitalization for infections. The increased risk of hospitalization for mycobacterial infections illustrates the potential bilateral relationship between the two conditions. Vaccination against respiratory pathogens and herpes zoster virus may help prevent some hospitalizations in pSS patients.KEY MESSAGESPrimary Sjögren's syndrome (pSS) increases hospitalization risk for community infections: bronchopulmonary, skin, dental, ear-nose-throat, intestinal infections and pyelonephritis.Hospitalizations for zoster and mycobacterial infections are also increased in this population.Dedicated preventive measures and vaccination campaigns could decrease the burden of infections in pSS patients.
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