Development and validation of a novel non-invasive test for diagnosing fibrotic non-alcoholic steatohepatitis in patients with biopsy-proven non-alcoholic fatty liver disease.
Feng GaoJiao-Feng HuangKenneth I ZhengXiao-Yan PanHong-Lei MaWen-Yue LiuChristopher D ByrneGiovanni TargherYang-Yang LiYong-Ping ChenWah-Kheong ChanMing-Hua ZhengPublished in: Journal of gastroenterology and hepatology (2020)
Our novel nomogram (combining MACK-3, platelet count and MetS) shows promising utility for diagnosing fibrotic NASH. The sequential combination of this nomogram and vibration-controlled transient elastography limits indeterminate results and reduces the number of unnecessary liver biopsies.