Predictors and outcomes of dose reduction of methotrexate and cyclosporin graft-versus-host disease prophylaxis following allogeneic haemopoietic cell transplantation.

Radha Ramanan Andrew B M LimJoanne L C TanRahul D BarmanrayKate MasonJenny CollinsMatthew HillmanJeffrey SzerAshish BajelDavid Ritchie

Published in: Internal medicine journal (2022)

Our findings suggest dose alteration in MTX and CYA GVHD prophylaxis is associated with adverse survival outcomes in alloHCT, without a significant impact on GVHD rates.

Keyphrases

cell therapy
allogeneic hematopoietic stem cell transplantation
stem cell transplantation
single cell
bone marrow
high dose
stem cells
acute myeloid leukemia
emergency department
adipose tissue
low dose
mesenchymal stem cells
hematopoietic stem cell
weight loss
drug induced