Resveratrol and insulin association reduced alveolar bone loss and produced an antioxidant effect in diabetic rats.
Fabiano Ribeiro CiranoAndréia Manetta MolezFernanda Vieira RibeiroHoward C TenenbaumMonica Grazieli CorrêaMônica Grazieli CorrêaSuzana Peres PimentelPublished in: Journal of periodontology (2020)
RSV reduced the progression of EP and the levels of NADPH oxidase. Co-treatment with RSV and insulin reduced the levels of pro-inflammatory factors (either proteins or mRNA) and increased the levels of SOD. The data also demonstrated that treatment with RSV and INS alone or in combination had beneficial effects on bone loss.