Enhanced immunovirological response in women compared to men after antiretroviral therapy initiation during acute and early HIV-1 infection: results from a longitudinal study in the French ANRS Primo cohort.
Sophie NovelliPierre DelobelOlivier BouchaudVeronique Avettand-FenoelPascale FialaireAndré CabiéFaouzi SoualaFrançois RaffiPilartxo CatalanLaurence WeissLaurence MeyerCécile GoujardPublished in: Journal of the International AIDS Society (2020)
The high level of immune recovery and decrease in total HIV DNA levels achieved after ART initiation during AHI reinforce the importance of early diagnosis of HIV infection and immediate ART initiation. The immunological benefit of being female increased throughout prolonged ART duration, which may give women additional protection from adverse clinical events and premature ageing.
Keyphrases
- antiretroviral therapy
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv infected patients
- hiv aids
- polycystic ovary syndrome
- pregnancy outcomes
- liver failure
- circulating tumor
- breast cancer risk
- cervical cancer screening
- type diabetes
- cell free
- single molecule
- insulin resistance
- drug induced
- emergency department
- metabolic syndrome
- adipose tissue
- skeletal muscle
- acute respiratory distress syndrome
- hepatitis c virus
- nucleic acid