Rapid Detection of the mt3243A > G Mutation Using Urine Sediment in Elderly Chinese Type 2 Diabetic Patients.

Yinan ZhangXiujuan DuXinqian GengChen ChuHuijuan LuYixie ShenRuihua ChenPingyan FangYanmei FengXiaojie ZhangYan ChenYanping ZhouCong-Rong Wang Weiping Jia

Published in: Journal of diabetes research (2017)

The occurrence of mt3243 A > G mutation was 0.2% in Chinese elderly type 2 diabetic patients. Moreover, detection of mt3243 A > G mutation in urine sediment with high-resolution melting (HRM) curve and pyrosequencing is feasible in molecular genetic diagnosis.

Keyphrases

high resolution
heavy metals
middle aged
risk assessment
mass spectrometry
genome wide
gene expression
dna methylation
copy number
single molecule
organic matter
liquid chromatography