Pericranial Muscle Stiffness, Pain Thresholds, and Tenderness during a Treatment Cycle of OnabotulinumtoxinA for Chronic Migraine Prevention.

Sebastian Worsaae DalbyJeppe Hvedstrup Louise Ninett Carlsen Sait AshinaLars BendtsenHenrik Winther Schytz

Published in: Diagnostics (Basel, Switzerland) (2024)

The findings suggest that BoNT-A leads to the desensitization of cutaneous and muscle nociceptors in the head and neck regions, whereas muscle relaxation might not be an important part of the anti-migraine effect.

Keyphrases

skeletal muscle
chronic pain
pain management
neuropathic pain
single molecule
spinal cord