Risk of Depression during Menopause in Women from Poland, Belarus, Belgium, and Greece.

The differences between the development of perimenopausal-related symptoms across countries were statistically significant. The incidence and severity of depression showed statistically significant differences between the countries studied-the highest was in Belarus and the lowest in Poland. Depression levels were not differentiated by subjects' age or the use of hormone therapy but by subjects' education. In Poland and Belarus, increased menopausal pain measured by the Kupperman Index altered levels of depression; in Belgium, there were no such correlations, and in Greece, the correlation was statistically significant, but its strength was negligible. A clearer correlation of the effects of development in menopausal symptoms on the level of depression was shown when measured with the MRS scale-in Greece and Belgium, the correlation was relatively weak, but in Poland and Belarus, it was relatively high.