Cardioprotective Effect of (Z)-2-Acetoxy-3-(3,4-Dihydroxyphenyl) Acrylic Acid: Inhibition of Apoptosis in Cardiomyocytes.

Wei Guo Zhi-Jun WangHao JueChunnan DongCheng Yang

Published in: Cardiovascular therapeutics (2020)

These data demonstrated that (Z)-2-acetoxy-3-(3,4-dihydroxyphenyl) acrylic acid possesses potent cardioprotective effects against cardiac injury in a rat model of heart failure, which is mediated, at least in part, by suppression of the inflammatory and cell apoptosis responses.

Keyphrases

heart failure
oxidative stress
left ventricular
cell proliferation
endoplasmic reticulum stress
electronic health record
cell death
cell cycle arrest
atrial fibrillation
big data
machine learning
artificial intelligence
cardiac resynchronization therapy
endothelial cells
deep learning