Disrupted executive cerebro-cerebellar functional connectivity in alcohol use disorder.
Laura C RiceMackenzie T LanganDominic T ChengYi-Shin SheuJutta PeterbursJun HuaQin QinJessica J RileeMonica L FaulknerJoanna R MathenaCynthia A MunroGary S WandMary E McCaulJohn E DesmondPublished in: Alcohol, clinical & experimental research (2023)
Our results show less engagement of the FPN in individuals with AUD than in CTL. FC strength within this network was positively associated with performance on the WCST. These findings suggest that long-term heavy drinking alters cerebro-cerebellar FC, particularly within networks that are involved in executive function.